Category: Uncategorized

H. D. Elphinstone Secondary School Gibsons, BC, Canada Background In 1943 the Myers-Briggs personality test was developed in the United States by Katharine Cook Briggs and her daughter Isabel Briggs Myers. When Isabel introduced her fiance to her mother Katherine, she began researching people’s different temperaments. Katherine found that Isabel’s fiance didn’t view the world…

Levi Cottrell, Elphinstone Secondary School, Gibsons, BC, Canada. Previous research has shown a ‘face-naming’ effect, where humans and machine learning algorithms are able to guess the name of a person given only their face and 4-5 name options at an accuracy greater than random chance. This effect was previously studied in French and Israeli contexts,…

Eating disorders are characterized as behavioral conditions, stemming from unhealthy eating habits that can have severe consequences for a person’s physical and emotional well-being. Some of the most common types of eating disorders include: Anorexia, Bulimia, and Binge eating. Anorexia is among the deadliest mental health illnesses. People with this condition  typically have a fear…

Abstract  Cognitive Behavioral Therapy (CBT) is a well-established treatment for depression. The following article reviews CBT’s effectiveness, compares it to other treatments, and explores its applications across different populations.  Introduction  Depression is a widespread mental health issue. According to the World Health Organization (WHO), more than 280 million people worldwide suffer from depression. CBT, developed…

Abstract Alzheimer’s Disease (AD) is a major global health concern characterized by cognitive decline and memory loss. While the exact causes of AD remain elusive, a combination of genetic, environmental, and lifestyle factors are implicated. The Mediterranean diet, known for its plant-based foods, healthy fats, and moderate fish and poultry consumption, has shown potential neuroprotective…

Intrauterine growth restriction (IUGR) is when a fetus does not reach its expected size during pregnancy and is assigned a birth weight or length below the 10th percentile for its age. IUGR can bring significant risks to neonatal health and has long-term consequences on metabolic functions. The understanding of metabolic changes due to IUGR is…

Abstract Alzheimer’s is a progressive disorder that causes deterioration to the brain causing the individual to suffer memory loss and loss of mental functions. The number of Americans dying from Alzheimer’s disease is rising over time, it is currently the seventh most common cause of death in the country. Almost 6 million Americans suffer from…

Abstract   Alzheimer’s disease (AD) is a progressive neurodegenerative disorder marked by amyloid-beta (Aβ) plaque accumulation, cognitive decline, and behavioral changes. Current treatments offer only symptomatic relief and have largely failed to alter disease progression, emphasizing the need for novel therapeutic approaches. This study evaluated the efficacy and safety of a novel Aβ aggregation inhibitor…

Abstract  In recent decades, there has been a growing realization of the effect of gut health and microbiota on mental health, particularly mood disorders. This paper aims to delve into the mechanisms through which gut microbiota affects mood disorders, focusing on the production and regulation of neurotransmitters. The primary objective of this paper is to…

CTE is detrimental to the well-being of athletes. Despite this revelation, there is no known cure and a lack of development regarding the implications of this condition. Therefore, the objective of this study is to uncover how, despite the rigorous symptoms of this disease, the public lacks crucial knowledge of CTE and the necessary treatments…

Abstract Melanoma, a particularly aggressive form of skin cancer, is known for its poor prognosis in advanced stages due to its tendency to metastasize and develop resistance to treatment. Originating from melanocytes, melanoma is driven by several genetic mutations that lead to aberrant signaling and uncontrolled cell proliferation. Mutations in certain genes can drive the…

Abstract Traditional drug discovery is time-intensive and costly, often spanning over a decade and incurring billions in expenses. This study introduces a novel machine learning pipeline tailored to predict and optimize inhibitors for Enhancer of Zeste Homolog 2 (EZH2), a critical epigenetic target implicated in cancer progression. Leveraging curated datasets from repositories like the Protein…

Abstract Epigenetics refers to heritable modifications in gene expression or cellular phenotype that occur without changes to the underlying DNA sequence. Unlike irreversible genetic abnormalities, epigenetic modifications are dynamic and reversible, making them promising therapeutic targets. These changes, including DNA methylation, histone modifications, and non-coding RNA interactions, regulate key cellular functions such as differentiation, proliferation,…

Neurodegenerative diseases (NDs) are conditions commonly characterized by significant physiological degeneration present in the brain and nervous systems. Despite persistent efforts from scientists and physicians for decades around the world, a definite solution for these disorders has yet to be discovered. Over 600 neurodegenerative diseases have been recorded, of those the most common conditions include…

Abstract Neuroplasticity, defined as the brain’s ability to reorganize itself by forming new neural connections throughout life, is fundamental to development, learning, memory, and recovery from brain injuries. This paper provides a comprehensive review of the mechanisms underlying neuroplasticity, including synaptic plasticity, neurogenesis, and the role of glial cells in modulating neuronal circuits. The authors…

Abstract The complications of illicit drugs on the brain are eclectic and complex. This article delves specifically into the effects incurred on dopamine pathways and production by illegal drugs and how those effects present themselves in the brain. All illicit drugs pose the risk of developing an addiction, a highly prevalent topic discussed in this…

Abstract Individuals with unmanaged diabetes have a much higher risk of developing peripheral neuropathy. With cases of diabetes continuing to spike around the world, more people are living with nerve damage that may progressively get worse. One of the strongest possibilities as to how diabetes may lead to peripheral neuropathy is related to any damage…